Enzymes and Inhibitors
Sigma Aldrich Fine Chemicals Biosciences Taka Diastase from Aspergi100G
TAKA Taka Diastase from Aspergi100G
ABclonal Technology Acetyl-CoA Carboxylase
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA the rate-limiting step in fatty acid synthesis There are two ACC forms alpha and beta encoded by two different genes ACC-alpha is highly enriched in lipogenic tissues The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA Multiple alternatively spliced transcript variants divergent in the 5 sequence and encoding distinct isoforms have been found for this gene
Cayman Chemical Oleoyl-D-lysInsodIum salt 1mg
An inhibitor of GlyT2a; selectively inhibits GlyT2a (IC50 = 48.3 nM) over GlyT1b (IC50 = >3,000 nM) in Xenopus oocytes expressing the human transporters; reduces allodynia in a nerve ligation rat model of neuropathic pain at 30 mg/kg, i.p.
![Abcam Anti-1, 3 beta glucan antibody [2G8]](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC3456805.png-250.jpg)
Abcam Anti-1, 3 beta glucan antibody [2G8]
Mouse monoclonal [2G8] to 1, 3 beta glucan
The product is subject to the following: Abcam Restricted Use Statement
Aldevron Guanylyltransferase, 1750ug
1750ug dispense of Guanylyltransferase. Guanyltransferase (GT), also known as Vaccinia Capping Enzyme (VCE), catalyzes addition of 7-methylguanylate cap structures (Cap 0) to the 5’ end of RNA in three steps:
Reactions 1 & 2: Conversion of an RNA substrate pppN(pN)n to GpppN(pN)n with increasing amounts of enzyme was visualized by gel electrophoresis (uncapped, lower band; capped, upper band). One unit (U) is the amount of enzyme activity that caps 50% of a 5’-ppp oligo in 30 minutes at 37°C.
Reaction 3: Methyl transfer from SAM to GpppN(pN)n producing SAH and cap-0 mRNA was measured using the EPIgeneousTM Methyltransferase Assay (Cisbio). One unit (U) is the amount of enzyme activity that produces 1 pmol of SAH from SAM in 30 minutes at 37°C using cap-0 substrate.
Aldevron Ribonuclease Inhibitor, 2500ug
2500ug dispense of Ribonuclease Inhibitor (Rnase Inhibitor). Ribonuclease Inhibitor is a potent, noncompetitive inhibitor of pancreatic-type ribonucleases including ribonucleases A, B and C.
Revvity Health Sciences Inc HTRF Phospho-total Lysis Buffer #1, 130 mL
HTRF Phospho-total Lysis Buffer #1, 130 mL
Ubpbio Ac-ANW-AMC, 5MG
Ac-ANW-AMC is a fluorogenic substrate of the chymotrypsin-like activity of proteasomes. This substrate is preferentially cleaved by immunoproteasomes compared to constitutive proteasomes. The AMC fluorescence can be detected by a fluorimeter or a plate reader using excitation/emission wavelengths at 360 nm/460 nm, respectively. This substrate can be used to determine the chymotrypsin-like activity of immunoproteasomes. Working concentration is 50 - 200 µM.
Biotium Aquaphile™ Coelenterazine h, lyophilized solid
Aquaphile coelenterazine native is a bioluminescence substrate in a special formulation format that is readily dissolved in water or PBS buffer for in vivo use.Properties: Yellow solid soluble in water or PBS buffer; Store at -20°C and protect from light; C26H21N3O3; MW: 423; [55779-48-1].
Medchemexpress LLC D-Luciferin 6 -methy 5mg | 24404-90-8 | 5 MG
D-luciferin 6'-methyl ether is a D-luciferin derivative that acts as a potent inhibitor of Photinus pyralis (firefly) luciferase. It is supplied as an off-white to light-yellow solid with high reported purity and is intended for use in luciferase inhibition studies and assay development.
- Potent Photinus pyralis luciferase inhibitor.
- Supplied as an off-white to light-yellow solid.
- Reported purity 99.55%.
- Molecular weight 294.35 g/mol; formula C12H10N2O3S2.
- Storage: 4°C; in solvent store -80°C (6 months) or -20°C (1 month); protect from light.
- Available in small solid quantities and in solution formats (10 mM in DMSO).
CPC Scientific DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS (trifluoroacetate salt) 5MG
Useful FRET substrate for a continuous fluorescence-based assay of the malaria aspartyl protease (plasmepsin). The peptide sequence ERNleFLSFP is derived from the cleavage site present in hemoglobin, with Nle as a substitution for Met to avoid potential oxidation related problems.SEQUENCE: DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS (trifluoroacetate salt)ONE-LETTER SEQUENCE: ERNleFLSFPMOLECULAR FORMULA: C76H98N16O15S1MOLECULAR WEIGHT: 1507.78STORAGE CONDITIONS: -20 5 CCAS REGISTRY NUMBER: [263718-22-5]SYNONYMS: RESEARCH AREA: AntimicrobialREFERENCES:M.Pennington et al., Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries, 5th International Symposium, London, p. 367, R.Epton, ed., Mayflower Scientific, (1998)S.Jiang et al., Antimicrob. Agents Chemother., 45, 2577 (2001)M.Stadler et al., J. Antibiot., 58, 775 (2005)SKU(s): MALA-001A, MALA-001B